Separation of Mineral from Brown Algae Extract using Micro Filtration (MF) and Ultra Filtration (UF) Membrans – Review

Mahreni Mahreni

Abstract


Brown algae (Phaeophyta) contain active compounds such as carbohydrates, proteins, phenolics, fats, pigments, vitamins and minerals. The mineral content of brown algae is around 8% to 40% consisting of cations Na+, K+, Mg++, Fe++, Zn++, Mn++ and heavy metals. Bioactive brown algae has many benefits, including Fucoidan as a cancer drug. The barrier of using Fucoidan as a medicine is its high mineral content. Therefore, the minerals must be separated. The extraction process of brown algae using various methods has been carried out with the aim of isolating the active component of Fucoidan that is free from minerals that will be an obstacle in utilizing the active component. This paper will describe some of the latest methods of extracting the active ingredients of brown algae and mineral separation processes using Micro Filtration (MF) and Ultra Filtration (UF) membrane. MF and UF membrane can separate small molecules such as cations (minerals) that can pass through the membrane so that macromolecules such as carbohydrates, fats, proteins, pigments, phenolics and vitamins can be separated from minerals and active ingredients in the absence of minerals can be obtained. The purpose of this paper is to provide research directions in the exploration of the active ingredients of brown algae for pharmaceutical and cosmetic applications without side effects caused by high metal or mineral content above the threshold value in brown algae extracts.

Keywords


Anti Kanker, Ekstraksi, Fucoidan, Mikro Filtrasi, Ultra Filtrasi

References


. Omid Ashayerizadeh, Behrouz Dastar, Parastoo Pourashouri. Study of antioxidant and antibacterial activities of depolymerized fucoidans extracted from Sargassum tenerrimum. International Journal of Biological Macromolecules 151 (2020) 1259–1266.

. Sivasankara Narayani, S. Saravanan, J. Ravindran, M.S. Ramasamy, J. Chitra. In vitro anticancer activity of fucoidan extracted from Sargassum cinereum against Caco-2 cells. International Journal of Biological Macromolecules 138 (2019) 618–628.

. Asanka Sanjeewa, K.K., Jung-Suck Lee, Won-Suck Kim, You-Jin Jeon. The potential of brown-algae polysaccharides for the development of anticancer agents: An update on anticancer effects reported for fucoidan and laminaran. Carbohydrate Polymers 177 (2017) 451–459.

. Artem S. Silchenkoa, Anton B. Rasina, Mikhail I. Kusaykina, Anatoly I. Kalinovsky, Zhang Miansong, Liu Changhengb, Olesya Malyarenko, Anastasiya O. Zueva, Tatyana N. Zvyagintseva, Svetlana P. Ermakova. Structure, enzymatic transformation, anticancer activity of fucoidan and sulphated fucooligosaccharides from Sargassum horneri. Carbohydrate Polymers 175 (2017) 654–660.

. Beatriz Gullón, Mohammed Gagaoua, Francisco J. Barbac, Patricia Gullón, Wangang Zhang, José M. Lorenzo. Seaweeds as promising resource of bioactive compounds: Overview of novel extraction strategies and design of tailored meat products. Trends in Food Science & Technology 100 (2020) 1–18

. Jong-il Choi, Sung Gu Lee, Se Jong Han, Minho Cho, Pyung Cheon Lee. .Effect of gamma irradiation on the structure of fucoidan. Radiation PhysicsandChemistry100(2014)54–58.

. Eduardo Caballero, Agustín Flores, Araceli Olivares. Sustainable exploitation of macroalgae species from Chilean coast: Characterization and food applications. Algal Research 57 (2021) 102349.

. C´eline Lavergne, Paula S.M. Celis-Pla, Audran Chenu, Fernanda Rodríguez-Rojas, Fabiola Moenne, María Jos´e Díaz, María Jesús Abello-Flores, Patricia Díaz, Ignacio Garrido, Paulina Bruning, Marcelo Verdugo, M. Gabriela Lobos, Claudio A. Saez. Macroalgae metal-biomonitoring in Antarctica: Addressing the consequences of human presence in the white continent. Environmental Pollution, 292 (2022), 118365.

. Biswajita Pradhan, Prajna Paramita Bhuyan, Srimanta Patra, Rabindra Nayak, Pradyota Kumar Behera, Chhandashree Behera, Akshaya Kumar Behera, Jang-Seu Ki, Mrutyunjay Jena. Beneficial effects of seaweeds and seaweed-derived bioactive compounds: Current evidence and future prospective. Biocatalysis and Agricultural Biotechnology, 39 (2022), 102242.

. Carlos Vaamonde-García, Noelia Fl´orez-Fern´andez, María Dolores Torres, María J. Lamas-V´azquez, Francisco J. Blanco, Herminia Domínguez, Rosa Meijide-Faílde. Study of fucoidans as natural biomolecules for therapeutical applications in osteoarthritis. Carbohydrate Polymers 258 (2021) 117692.

. Catarina Oliveira, Nuno M. Neves, Rui L. Reisa, Albino Martins, Tiago H. Silva. A review on fucoidan antitumor strategies: From a biological active agent to a structural component of fucoidan-based systems. Carbohydrate Polymers 239 (2020) 116131

. Anjin Chen, Ying Lan, Jingwen Liu, Fang Zhang, Lijuan Zhangc, Bafang Lia, Xue Zhao, The structure property and endothelial protective activity of fucoidan from Laminaria japonica International Journal of Biological Macromolecules 105 (2017) 1421–1429.

. Yuan Yao, Evelyn K.F. Yim. Fucoidan for cardiovascular application and the factors mediating its activities. Fucoidan for cardiovascular application and the factors mediating its activities. Carbohydrate Polymers 270 (2021) 118347.

Roza V. Usoltseva, Olesya S. Malyarenko, Stanislav D. Anastyuk, Natalia M. Shevchenko, Artem S. Silchenko, Tatiana N. Zvyagintseva, Vladimir V. Isakov, Pham Duc Thinh, Huynh Hoang Nhu Khanh, Cao Thi Thuy Hang, Dinh Thanh Trung, Svetlana P. Ermakova. The structure of fucoidan from Sargassum oligocystum and radiosensitizing activity of galactofucans from some algae of genus Sargassum. International Journal of Biological Macromolecules, 183 (2021), 1427-1435.

. Xue Liu, Xiangyu Xi, Airong Jia, Miansong Zhang, Tingting Cui, Xinfeng Bai, Yaping Shi, Changheng Liu. A fucoidan from Sargassum fusiforme with novel structure and its regulatory effects on intestinal microbiota in high-fat diet-fed mice. Food Chemistry, 358 (2021), 129908.

. Weiqiang Wang, Zhonglin Chen, Yanchi Zhou, Pengwei Yan, Jimin Shen, Shuyu Wang, Jing Kang, Jingyi Sun, Zhe Wang, Yanbin Tong Catalytic ozonation with silicate-based microfiltration membrane for the removal of iopamidol in aqueous solution. Separation and Purification Technology, 257 (2021), 117873.

. Wanyuan Gui, Jingru Liu, Xiping Song, Hui Zhang, Junpin Lin, Benli Luan. A new microfiltration membrane with three-dimensional reticular architecture for Nano-pollutants removal from wastewater. Progress in Natural Science: Materials International, 31 (2021), 414-419.

. Wang, Y., Li, D., Li, J., Li, J., Fan, M., Han, M., Liu, Z., Li, Z., Kong, F., Metal organic framework UiO-66 incorporated ultrafiltration membranes for simultaneous organic matter and heavy metal ions removal, Environmental Research (2022), doi: https://doi.org/10.1016/ j.envres.2021.112651.

. Randeep Singh, Vikranth Volli, Lokesh Lohani, Mihir Kumar Purkait. Polymeric ultrafiltration membranes modified with flyash based carbon nanotubes for thermal stability and protein separation. Case Studies in Chemical and Environmental Engineering, 4 (2021), 100155.

Qingchen. Lu, N. Li, X. Zhang, Supramolecular recognition PVDF/PVA ultrafiltrationmembrane for rapid removing aromatic compounds from water, Chemical Engineering Journal (2021), doi:https://doi.org/10.1016/j.cej.2021.132889.

. Viruja Ummat, Saravana Periaswamy Sivagnanam, Gaurav Rajauria, Colm O’Donnell, Brijesh Kumar Tiwari. Advances in pre-treatment techniques and green extraction technologies for bioactives from seaweeds. Trends in Food Science & Technology, 110 (2021), 90-106.

. Smita Singh, Deepak Kumar Verma, Mamta Thakur, Soubhagya Tripathy, Ami R. Patel, Nihir Shah, Gemilang Lara Utama, Prem Prakash Srivastav, Juan Roberto Benavente-Vald´es, Monica ´ L. Chavez-Gonzalez, Cristobal Noe Aguilar. Supercritical fluid extraction (SCFE) as green extraction technology for high-value metabolites of algae, its potential trends in food and human health. Food Research International, 150 (2021), 110746.

. Venansius G.P. Putra, Selma Mutiarahma, Weni Chaniago, Puji Rahmadi,Dedy Kurnianto, Chusnul Hidayat, Ceferino Carrera, Miguel Palma, Widiastuti Setyaningsih. An ultrasound-based technique for the analytical extraction of phenolic compounds in red algae. Arabian Journal of Chemistry (2022) 15, 103597.

. Aravind, S., Debabrata Barik, P. Ragupathi, G. Vignesh. Investigation on algae oil extraction from algae Spirogyra by Soxhlet extraction method. Materials Today: Proceedings 43 (2021) 308–313.

. Raúl I. Aravena, Jos´e M. del Valle, Juan C. de la Fuente. Supercritical CO2 extraction of aqueous suspensions of disrupted Haematococcus pluvialis cysts. The Journal of Supercritical Fluids 181 (2022) 105392.




DOI: https://doi.org/10.31315/e.v19i1.6653

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